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Objectives: We would like to report a case in which a COVID-19 patient who was transferred to our hospital due to a lack of medical resources due to the COVID-19 outbreak in Daegu, South Korea, on February, 2020, underwent double lung transplantation after 110 days with VV-ECMO support and performed double lung re-transplantation 865 days after lung transplantation. Method(s): ECMO was performed on a total of 69 patients with COVID-19-related acute circulatory/ respiratory failure from February 2020 to December 2022. Among them, 16 patients were registered for lung transplantation, and 5 out of 16 registered patients performed lung transplants. One in five people who performed lung transplantation performed retransplantation on the 865thday after transplantation. Result(s): A 52-year-old female patient was transferred to our hospital, and VV-ECMO was performed the next day. The double lung transplantation was performed 112 days after hospitalization and was discharged 238 days after surgery. 668 days after lung transplantation, home O2 was applied as bronchitis obliterans syndrome, and her lung function deteriorated rapidly later, and re-transplantation was decided. In the patient;s HLA test, HLA class I cPRA% was 32% and HLA class II cPRA% was 100%. Desensitization was performed six times plasmapheresis with administrating Botezomib and immunoglobulin, and then re-transplantation was performed on the 865th day after lung transplantation. The patient has maintained her daily life without any special complications other than the occurrence of central DI after surgery. The pathological findings of the lung previously transplanted to the patient were acute rejection (ISHLT grade A2), chronic airway rejection (ISHLT grade C1, B0), and chronic vascular rejection (ISHLT grade D1). Conclusion(s): The long term result of patients who performed lung transplantation with COVID 19 related respiratory failure is still unknown. Therefore, even patients who have undergone long-term VV-ECMO support due to COVID 19 related respiratory failure are expected to achieve good results if lung transplantation is needed by carefully approaching and treating with a multidisciplinary approach.
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Medical waste has been excessively generated in various medical facilities due to COVID-19, and its treatment has become an important concern. Previously, an optimized medical waste sterilization and shredding system was developed for hospital scale but due to increased demand, it is necessary to scale such a system for different facilities. Therefore, in this paper, a sensitivity analysis for the design variables of the shredding system has been conducted and a surrogate model is developed for stress estimation. The surrogate model was generated using LHS (Latin hypercube sampling), which can represent the overall information of the design domain with a limited number of samples. The surrogate model was then used to increase the number of samples for sensitivity analysis which helped in reducing the computational time for finite element analysis. The sensitive variables for the shredder system were then estimated using sensitivity analysis. Consequently, an efficient design framework for various capacities of medical waste shredder was suggested using sensitivity analysis and a data-driven surrogate model.
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With the increasing number of foreigners residing in Korea, there is a need for further research on medical service satisfaction for this demographic. Therefore, this study aimed to analyze the impact of medical service quality on customer satisfaction and revisit intention of foreigners in Korea during the COVID-19 pandemic. An online survey was conducted from 15 March to 15 May 2022 to gather data from foreign residents in Korea. A total of 201 questionnaires were analyzed using IBM SPSS Statistics 26.0 and Smart PLS3.0 for empirical analysis. The results of the study demonstrate that reliability, empathy, and COVID-19 regulations (excluding responsiveness, assurance, and tangibles) positively impact customer satisfaction with medical services. Additionally, customer satisfaction with medical services positively affects revisit intention. Furthermore, variables, such as nationality and medical department, show average differences. These findings suggest that hospitals should focus on COVID-19 prevention and the quality of medical services, while also taking into account unique characteristics, such as nationality and medical department. This study provides essential reference data for medical institutions exposed to infinite competition, informing management strategies to increase customer satisfaction and revisit intention during COVID-19. © 2023 by the authors.
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Purpose Modern society is facing many changes due to the Fourth Industrial Revolution. In addition, as daily life became non-face-to-face due to the prolonged COVID-19, the use of non-face-to-face digital devices using information and communication technology was further accelerated. Due to these changes, various digital services such as telemedicine and mobile financial services could be used, and functions such as work and school could be maintained even in the COVID-19 situation. However, the rapid transition to an information society further revealed the information vulnerability of the elderly. This is because digital literacy, which is a key competency to adapt in the information society, has acted as a limitation for the elderly, who are vulnerable to information, and their ability to use digital devices. Many previous studies pointed out the low level of informatization in the elderly and various problems that may arise from this(H. S. Kim, J. S. Shim, 2019;NIA, 2020;S. Y. Lee, 2021). The elderly, who are digital vulnerable, are feared to intensify social isolation in the current network era, which is likely to have a negative impact on mental health (Park et al., 2022). Social participation is a representative factor that can control mental health(Kim et al., 2019). Social participation has been verified as a factor that can improve life satisfaction, such as self-realization and overcoming alienation. Therefore, this study attempts to verify the moderated mediating effect of social participation through depression in the relationship between digital literacy and life satisfaction of the elderly. Method This study analyzed 8,664 elderly aged 65 or older who responded to the 2020 Senior Survey conducted jointly with the Korea Institute for Health and Social Affairs and the Ministry of Health and Welfare, and attempted to verify the moderated mediating effect using SPSS 23.0 and SPSS PROCESS 3.4.1. The verification of the research model proceeds in a total of three steps. First, the mediating effect of depression in the relationship between digital literacy and life satisfaction of the elderly is verified using the bootstrapping method. Second, in order to examine the moderating effect of social participation in the relationship between depression and life satisfaction, multiple regression analysis is conducted after averaging. Finally, in the relationship between digital literacy and life satisfaction, the moderated mediating effect of depression is verified by social participation. Results and Discussion The main findings are as follows. First, it was verified that depression had a partial mediating effect in the relationship between digital literacy and life satisfaction. Second, it was verified that social participation had a moderating effect in the relationship between depression and life satisfaction. Third, it was verified that in the relationship between digital literacy and life satisfaction, the mediating effect of depression decreases as social participation increases. This study is meaningful in that it confirmed the effectiveness of digital literacy and social participation as a way to increase life satisfaction of the elderly. Therefore, it is necessary to prepare an informatization education plan to improve the level of digital device use of the elderly, and to provide opportunities to continuously participate in society. These research results will be the basis for suggesting ways to solve problems such as digital information gap and digital inequality for the elderly by establishing welfare for the elderly, education for the elderly, and policies to improve self-efficacy. © 2022, Gerontechnology. All Rights Reserved.
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Coronavirus disease 2019 (COVID-19) in patients with underlying diseases, is associated with high infection and mortality rates, which may result in acute respiratory distress syndrome and death. Mucopolysaccharidosis (MPS) type II is a progressive metabolic disorder that stems from cellular accumulation of the glycosaminoglycans, heparan, and dermatan sulfate. Upper and lower airway obstruction and restrictive pulmonary diseases are common complaints of patients with MPS, and respiratory infections of bacterial or viral origin could result in fatal outcomes. We report a case of COVID-19 in a 16-year-old adolescent with MPS type II, who had been treated with idursulfase since 5 years of age. Prior to infection, the patient’s clinical history included developmental delays, abdominal distension, snoring, and facial dysmorphism. His primary complaints at the time of admission included rhinorrhea, cough, and sputum without fever or increased oxygen demand. His heart rate, respiratory rate, and oxygen saturation were within the normal biological reference intervals, and chest radiography revealed no signs of pneumonia. Consequently, supportive therapy and quarantine were recommended. The patient experienced an uneventful course of COVID-19 despite underlying MPS type II, which may be the result of an unfavorable host cell environment and changes in expression patterns of proteins involved in interactions with viral proteins. Moreover, elevated serum heparan sulfate in patients with MPS may compete with cell surface heparan sulfate, which is essential for successful interaction between the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and the host cell surface, thereby protecting against intracellular penetration by SARS-CoV-2.
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The long-term pandemic caused by COVID-19 has changed many aspects of the work environment. Companies stalled to seriously consider telework and many have actually adopted it as an alternative way to work, hi fact 73.9% of overseas architect firms are using the telework while domestic architect firms shows no signs of introducing it yet. Various causes are suggested as to why the telework is not yet implemented in architectural practice even with the necessity of introduction, they are only unverified speculations and in order to understand the causes and solve the problems, a sophisticated analysis of the cause is required, hi addition, telework is not just a temporary option in pandemic situation but it needs to be established as another type of work in arcliitectiiral industiy in preparation for similar situation that may occur in the future. Therefore, this study aims to derive the impediments recognized by architect in introducing telework into domestic architect offices, and based on the results of the analysis from the derived factors, it was attempted to find a way to activate telework. Through the literature review, it is conformed that the research regarding the telework of architect office was insufficient and for this reason, telework consideration factors were derived from related studies targeting general companies. The questionnaire was prepared in consideration of the derived factors and the characteristics of the design work, and it was conducted at a time when the government's social distancing guidelines and telework recommendations were made. The study was conducted using the responses of 103 persons working in architect offices of the metropolitan area. As a result, it was confirmed that the cause of hindrace for teleworking perceived by the workers in the architect office was due to the specific characteristics of the design work, and it was confimed that the communication of visual information was the biggest hindrance factor ill the design work, hi addition, as a result of ANOVA on the questionnaire results, it was confirmed that there was a difference in the perceptions of architects about telework, and the main difference came from the work position and project experience. Afterwards. through factor analysis, specific directions were presented for three aspects: communication of design work when working from home, support within the organization, and establishment of IT infrastructure as a way to revitalize it. © 2022 Architectural Institute of Korea
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Background/Aim: It is easy to predict that the actual COVID-19 pandemic would have had a negative impact on cancer screening activities and the outcomes of screenings, but to date, real-time population-based evidence to substantiate this concern is very scarce. In this study, to understand the changes in the behavior and performance of CRC screening following the COVID-19 pandemic, the indicators of CRC screening processes and outcome measures were compared with both monthly data in 2019 and monthly changes focusing on the peaks that appeared in 2020. Method: This population-based nationwide study used fecal immunochemical test (FIT) and colonoscopy claims data from the Korean National Health Insurance System (NHIS) from 2019 to 2020. Data were analyzed from 15,867,759 subjects in 2019 and 16,155,930 subjects in 2020. We compared the data of CRC screening (FIT/ colonoscopy) of the COVID-19 pandemic period (2020) with those of the same period of 2019. Result: In the COVID-19 period, 3,445,660 (21.3%) subjects underwent FIT, whereas in 2019, 6,490,707 (40.9%) subjects performed FIT (almost 2-fold). Participation rate in colonoscopy after FIT positive fell in 2020 by 36.0% compared with the average rate recorded in 2019 (44.5%). In particular, it was confirmed that the participation rate of the CRC screening further decreased immediately after the COVID-19 peak periods (first and second wave: March 2020 and August 2020). Conclusion: The overall adherences to CRC screening tests decreased substantially during COVID-19 pandemic. Therefore, urgent modulation for not only easier access but also planning a restart for CRC screening is needed to address the growing burden of under-detected CRC in Korea.
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COVID-19 is considered as a major public health problem caused by the SARS CoV-2. This Viral infection is known to induce worldwide pandemic in short period of time. Emerging evidence suggested that the transmission control and drug therapy may influence the preventive measures extensively as the host surrounding environment and pathogenic mechanism may contribute to the pandemic condition earlier in COVID-19 disease. Although, several animals identified as reservoir to date, however human-to-human transmission is well documented. Human beings are sustaining the virus in the communities and act as an amplifier of the virus. Human activities i.e., living with the patient, touching patient waste etc. in the surrounding of active patients or asymptomatic persons cause significant risk factors for transmission. On the other hand, drug target and mechanism to destroy the virus or virus inhibition depends on diversified approaches of drugs and different target for virus life cycle. This article describes the sustainable chemical preventive models understanding, requirements, technology adaptation and the implementation strategies in these pandemic-like situations. As the outbreak progresses, healthcare models focused on transmission control through disinfections and sanitization based on risk calculations. Identification of the most suitable target of drugs and regional control model of transmission are of high priority. In the early stages of an outbreak, availability of epidemiological information is important to encourage preventive measures efforts by public health authorities and provide robust evidence to guide interventions. Here, we have discussed the level of adaptations in technology that research professionals display toward their public health preventive models. We should compile a representative data set of adaptations that humans can consider for transmission control and adopt for viruses and their hosts. Overall, there are many aspects of the chemical science and technology in virus preventive measures. Herein, the most recent advances in this context are discussed, and the possible reasons behind the sustainable preventive model are presented. This kind of sustainable preventive model having adaptation and implementation with green chemistry system will reduce the shedding of the virus into the community by eco-friendly methods, and thus the risk of transmission and infection progression can be mitigated.
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Despite the proliferation of innovative technologies during the Fourth Industrial Revolution (4IR), there is a severe lack of quantitative and empirical studies that deal with the effectiveness of recently emerging technologies. This study examines the impact of employing core technologies of the 4IR on small and medium enterprises (SMEs). We used the firm-level cross-sectional data on Korean manufacturing SMEs, including the information on technology utilization. The stochastic production frontier estimation with selectivity correction is employed, besides matching technique to obtain unbiased estimates on technology efficiency. The empirical analysis finds that adopting emerging technologies enhances the productivity of SMEs. After observed and unobserved factors are controlled, the technical efficiency of adopters is higher by more than 26% on average, compared to non-adopters. Moreover, if the gap among production frontiers is considered, the difference in productivity would rise further. Additionally, a strategic alliance is a crucial route for SMEs to accept new technologies. Plain English Summary Adopting emerging technologies in the Fourth Industrial Revolution makes production process more efficient by more than 26% on average. This research using the data on Korean manufacturing small and medium enterprises (SMEs) revealed that new digital technologies have a significantly positive impact on the productivity improvement. More specifically, SMEs adopting emerging technologies like "AI," "Big Data," and "Robotics" in the production process have remarkably higher productivity by more than 26%, compared to non-adopters. This result suggests that digital transformation is an unparalleled opportunity for SMEs suffering from lower productivity attributed to some reasons like the outbreak of COVID-19 pandemic. Additionally, the government needs to establish a pan-government control tower and consider a variety of policy measures to promote SMEs to utilize advanced technologies in their production.
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China's shutdown due to COVID-19 in 2020 reduced air pollutant emissions, which is located on the windward side of South Korea. The positive temperature anomaly and negative zonal wind anomaly from northern Mongolia to South Korea through eastern China presented warm and stationary air masses during January and February 2020. Decreased concentrations of PM10, NO2, and O-3 were measured at Seokmo-ri and Pado-ri, located in the central-western region of South Korea, due to decreased emissions in China from January to March 2020. After China's shutdown from January to March 2020, in Pado-ri, the ratio of monthly average concentrations in that period with those of PM10 and O-3 in the last four years decreased by approximately 0.7-4.7% and 9.2-22.8%, respectively. In January 2020, during the Lunar New Year holidays in China, concentrations of PM10, NO2, and O-3 at Seokmo-ri and Pado-ri decreased just as much as it did during the same period in the last four years. However, average concentrations in January 2020 decreased before and after the Lunar New Year holidays in China when compared with those in January of the last four years. In Seokmori, ratios of actual and predicted values ((O) over bar (s)/M) for PM10, NO2, and O-3 concentrations were calculated as 70.8 to 89.7%, 70.5 to 87.1%, and 72.5 to 97.1%, respectively, during January and March 2020. Moreover, those of Pado-ri were 79.6 to 93.5%, 67.7 to 84.9%, and 83.7 to 94.6%, respectively. In January 2020, the aerosol optical depth (AOD) data showed a higher distribution than that of the last four years due to photochemical reactions in regions from northern Mongolia to eastern China and the Korean Peninsula. However, the decrease in AOD values compared with those of the last four years was attributed to the decrease in emissions of precursors that generate secondary aerosols in China during March 2020.
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The extent of viral spread and strategies in dealing with the COVID-19 pandemic have been different in each country. There are overall increased mental health concerns in many countries but it is unclear what the general public individuals who do not have heighten vulnerability to stressors for existing mental diseases or significant physical illnesses were experiencing during the pandemic. We evaluated the stressors and mental health of general public in South Korea that has a relatively low confirmed cases and deaths. Responses on the on-line survey questions were used to assess the mental and physical symptoms in association with individuals' reported stressors. Individuals with the symptoms of the generalized anxiety disorder (GAD) were reported in 58.9%, and major depression (MD) in 23.2%, mostly in minimal to mild degrees, cut-off scores of 5 and 10, respectively by the validated screening tools, GAD-7 and PHQ-9. Both GAD and MD symptoms were in 21.5% of the respondents. The total number of stress had significant association with the scores of GAD-7, PHQ-9, physical symptoms, sleep difficulties and resilience (p < 0.01). GAD scores were also associated with sleep difficulties (p < 0.01) and raising young children (p < 0.05). MD scores were associated with sleep difficulties, job-dissatisfaction, and educational level (p < 0.05). The limitations of the study include small sample size, usage of smartphone or email, potential under-reporting by stigma in the socio-cultural context and evolving nature of pandemic. We conclude that keeping careful watch for mental symptoms, stressors, sleep difficulties and other physical symptoms are important even for the individuals without previous mental illnesses during the pandemic era.
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The pandemic of Coronavirus diseases occurred in the Republic of Korea from 19 January 2020. By March 2020, Korea had reported the second largest number of Coronavirus patients in the world. On the anniversary date (2021), however, with a 51.3 M population, Korea has had 73.115 K patients with 1.283 K deaths, and this stands at 86th in the world. On average, Korea has 14.3 patients per 10,000 people. Air-parcel trajectory analysis and airflows show that in the general westerly region, air parcels and pollutants could flow out and in all directions. This suggests initially that Coronaviruses from source areas in China could transmit to many sink regions and sectors including 228 subdivided counties in Korea. However, there were only relatively small numbers of Coronavirus patients in western sea sides of the Korean Peninsula in comparison with large numbers of Coronavirus disease patients in cities and in eastern sides. In particular, three counties in Korea, including Ong-jin, Mooju and Chang-heung, have zero patients of Coronavirus diseases. This suggests that a long-distance transmission of Coronavirus from Wuhan and other infected cities in China to western Korea likely did not occur. Moreover, there was no evidence on the potential transmission of Coronavirus from neighboring large cities to the above-mentioned isolated counties in Korea which are only 10 ~ 50 km away. In the biosphere, during the transmission stage, the inactivation of Coronavirus by UV rays appeared to occur effectively in 30 ~ 120 min, in agreement with the result of satellite and modeling studies. In turn, the air transmission of Coronaviruses and pollution from China and neighboring cities in Korea apparently had no impact to cause Coronavirus diseases at the 228 counties in Korea. The infection and spreading of Coronavirus diseases to other people in Korea mainly appeared to occur in confined indoor air environments. With the absence and lack of UV rays in indoor environments, Coronaviruses would be active there for hours or days longer than in the outdoor environments.
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The COVID-19 pandemic has had a huge impact on every facet of life around the world. For many, the world has become a place of doubt and uncertainty as people struggle to cope with the changes coming in the wake of COVID-19 and seek to determine how best to respond. With ecological, economic, and ideological crises occurring alongside COVID-19, this study proposes religious education that emphasizes the value of life, promotes equality, and fosters global interconnectedness. This religious education provides an open, equal, and interconnected environment where learners can understand, discuss, and confront global problems for the common future.
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In a global pandemic, public health outcomes are not the only variables at stake. Also at stake are countries’ nation brands and influence, which hinge on how a country responded to the crisis. Based on a case study of a middle power, South Korea, one of the more successful COVID-19 national responses so far, we offer an exploratory conceptual explication of pandemic public diplomacy that is grounded in a normative framework of substance, information, trust, collaboration, and mutual benefit. Sentiment analyses of social media and international news media suggest that the country is perceived as a model on how to cope with the pandemic by international audiences. Unlike other public diplomacy contexts, pandemic public diplomacy challenge conventional assumptions about public diplomacy and nation branding. As nation-states confront a common enemy, how public diplomacy and nation branding play out in COVID-19—arguably the most socially disruptive event in modern history—helps to shed light on the dynamics of mutual interdependence in an interconnected yet competitive world fraught with fear, uncertainty, and information deficiency. © 2020, Springer Nature Limited.